地塞米松 - 蛋白质偶联物抗血清的制备及其性质
Production and properties of antisera to dexamethasone-protein conjugates.
作者信息
Dumasia M C, Chapman D I, Moss M S, O'Connor C
出版信息
Biochem J. 1973 Jun;133(2):401-4. doi: 10.1042/bj1330401.
Abstract
Antibodies to dexamethasone 21-hemisuccinate conjugated to bovine serum albumin were produced in rabbits. Antisera diluted 1:3000 bound 50% of 90pg of [1,2-(3)H]dexamethasone. The cross-reaction of the antisera with other synthetic and natural corticosteroids was measured.
摘要
用牛血清白蛋白偶联的地塞米松21-半琥珀酸酯免疫家兔，制备其抗体。将抗血清稀释1:3000，可结合90pg [1,2-(3)H]地塞米松的50%。测定了该抗血清与其他合成及天然皮质类固醇的交叉反应。
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