Rapaport J
Arch Dermatol. 1975 Jan;111(1):73-5.
In a case of giant keratoacanthoma of the nose, the lesion was extremely invasive, destroying the entire nose. Electrosurgical removal of the grossly abnormal tissue was followed by rapid recurrence on two occasions. Radiation therapy was not effective. The lesion healed after the use of bleomycin sulfate.
在一例鼻部巨大角化棘皮瘤病例中，病变具有极强的侵袭性，破坏了整个鼻子。对肉眼可见的异常组织进行电外科切除后，病变两次迅速复发。放射治疗无效。使用硫酸博来霉素后病变愈合。
