Kempf P, Brünner H
Res Exp Med (Berl). 1979 May 30;175(2):109-16. doi: 10.1007/BF01851817.
Total gastrectomy was performed on purebred beagle dogs and a 30--40 cm jejunal segment was grafted isoperistaltically between oesophagus and duodenum. Histological and histoautoradiographical examinations were carried out and the wall-thickness and the cell-transformation rate in the interponate determined. Despite the isoperistaltic substitute-stomach a muscular wall-hypertrophy of 140% of the interponated jejunum was found. The reason for this hypertrophy is thought to be the result of adhesions and the functional mechanical demands. Histoautoradiographical examinations confirmed that the regeneration time in the substitute-stomach decreased by 70% compared with the normal jejunum. The distinct reduction of cell regeneration in the regeneration in the interponated jejunum could be attributed to the considerable regression of the absorbent performance and to the increase in its mechanical exercises.
对纯种比格犬实施全胃切除术，并将一段30 - 40厘米的空肠段顺蠕动移植于食管和十二指肠之间。进行了组织学和组织放射自显影检查，并测定了植入段的壁厚和细胞转化率。尽管是顺蠕动替代胃，但仍发现植入空肠的肌壁肥大了140%。这种肥大的原因被认为是粘连和功能性机械需求的结果。组织放射自显影检查证实，替代胃中的再生时间与正常空肠相比减少了70%。植入空肠再生中细胞再生的明显减少可归因于吸收性能的显著退化及其机械活动的增加。
