Ranaweera A, Ford E J, Samad A R
Res Vet Sci. 1979 Jan;26(1):12-6.
Hypoglycaemic ketosis clinically resembling pregnancy toxaemia was induced by starvation in Clun Forest sheep pregnant with twins. Total glucose entry was measured by the continuous infusion of trace amounts of (2-3H) glucose before and after the induction of ketosis and 24 h after the intramuscular injection of the ketotic sheep with triamcinolone acetonide (0.5 mg/kg). The concentration of glucose in plasma fell significantly after the induction of ketosis and rose significantly after the injection of steroid. The total entry rate of glucose fell significantly after the induction of ketosis and rose, but no significantly, after steroid injection. It is suggested that the dose of steroid which was used may inhibit glucose utilisation by peripheral tissues. The induction of ketosis significantly reduced the duration of pregnancy but the steroid injection did not produce a significant additional effect.
怀有双胞胎的克伦森林羊通过饥饿诱导出临床上类似于妊娠毒血症的低血糖性酮症。在诱导酮症前后以及给酮症羊肌肉注射曲安奈德（0.5毫克/千克）24小时后，通过持续输注微量（2-³H）葡萄糖来测量葡萄糖的总进入量。诱导酮症后血浆葡萄糖浓度显著下降，注射类固醇后显著上升。诱导酮症后葡萄糖的总进入率显著下降，注射类固醇后虽有上升但不显著。提示所使用的类固醇剂量可能抑制外周组织对葡萄糖的利用。诱导酮症显著缩短了妊娠期，但注射类固醇并未产生显著的额外影响。
