Svanberg L, Astedt B
Cancer. 1975 May;35(5):1382-7. doi: 10.1002/1097-0142(197505)35:5<1382::aid-cncr2820350522>3.0.co;2-0.
Ascitic fluid samples from 19 patients with ovarian carcinoma, 3 with a benign ovarian tumor, and 5 with cirrhosis of the liver were examined for their content of coagulation factors and components of the fibrinolytic system. The concentration of trypsin inhibitors in the ascitic fluid was significantly higher in the presence of carcinoma. Large amounts of FDP were found in the ascitic fluid in all patients with malignant tumors, but not in the other two groups. Determination of FDP may therefore make it possible to differentiate between malignant and nonmalignant ascitic fluid.
对19例卵巢癌患者、3例卵巢良性肿瘤患者和5例肝硬化患者的腹水样本进行了凝血因子含量及纤维蛋白溶解系统成分的检测。癌存在时腹水中胰蛋白酶抑制剂的浓度显著更高。所有恶性肿瘤患者的腹水中均发现大量纤维蛋白降解产物（FDP），而其他两组未发现。因此，检测FDP可能有助于鉴别恶性腹水和非恶性腹水。
