Nordhus O
Scand J Thorac Cardiovasc Surg. 1979;13(2):147-52. doi: 10.3109/14017437909100982.
With the aid of an electromagnetic flowmeter and a mechano-electrical pressure transducer, peroperative renal artery blood flows and pressures in the aorta and the renal artery distal to the stenosis were measured in 48 patients with renovascular hypertension before and after renal artery reconstruction. Calculations of pressure difference across the stenosis and resistances over the stenosis and the renal parenchyma were made. There was a significant blood flow increase through the renal artery after arterial reconstruction in all patients, irrespective as to whether they were normotensive, improved or failures postoperatively. The pressure difference across the stenosis after reconstruction was eliminated in all 3 groups of patients. The highest resistances over both the stenosis and the renal parenchyma before arterial reconstruction were found in the normotensive group, but there was no significant variation between the 3 groups. After reconstruction, a significant decrease in resistance over the renal parenchyma was found in the normotensive and the improved group of patients. The resistance of the stenosis was higher than over the renal parenchyma only in the postoperatively normotensive patients. This indicates that the removal of a resistance over the renal artery stenosis, that is higher than that over the renal parenchyma, gives the most favourable long-term results concerning normalization of the blood pressure.
借助电磁流量计和机电压力传感器,对48例肾血管性高血压患者在肾动脉重建术前和术后测量了术中肾动脉血流以及主动脉和狭窄远端肾动脉的压力。计算了狭窄两端的压差以及狭窄处和肾实质的阻力。所有患者在动脉重建后肾动脉血流均显著增加,无论术后血压正常、改善还是未改善。三组患者重建后狭窄两端的压差均消失。动脉重建前,血压正常组在狭窄处和肾实质的阻力最高,但三组之间无显著差异。重建后,血压正常组和改善组患者肾实质的阻力显著降低。仅在术后血压正常的患者中,狭窄处的阻力高于肾实质。这表明,去除高于肾实质阻力的肾动脉狭窄阻力,在血压正常化方面可带来最有利的长期结果。