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Iodine-125--labeled estradiol: a gamma-emitting analog of estradiol that binds to the estrogen receptor.

作者信息

Hochberg R B

出版信息

Science. 1979 Sep 14;205(4411):1138-40. doi: 10.1126/science.472733.

Abstract

17 beta-[16 alpha-125I]Iodoestradiol has been synthesized by exchange of 16 beta-bromoestradiol with Na125I. The iodinated product is readily separated from the bromo reactant by column chromatography. It concentrates in the rat uterus in vivo and binds avidly and specifically to the uterine estrogen receptor in vitro.

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