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肽沉淀木质素磺酸对微生物产生的或作用于微生物的各种生物活性物质的体外作用。

The in vitro effects of peptide-precipitating lignosulphonic acids on various biologically active substances produced by or with action on microorganisms.

作者信息

Naess B, Sandvik O

出版信息

Acta Vet Scand. 1973;14(1):129-46. doi: 10.1186/BF03547416.

Abstract

The effects of lignosulphonic acids on colicins, coliphages, different antibiotics, ß-toxin of Staphylococcus aureus, lecithinases of Clostridium perfringens and of Bacillus cereus, hemolysins of Bacillus cereus and Escherichia coli, the bactericidal effect of lysolecithin and on specific and naturally occurring serum proteinase inhibitors have been studied. It was found that lignosulphonic acids distinctly inhibit the biological activities tested, with the possible exceptions of the inhibitory effects of serum antiproteinases, naturally occurring inhibitors in serum, and the bacteriolytic effect of coliphages. The inhibiting effects are discussed in relation to the use of animal fodder containing lignosulphonic acids, and to the appearance of a selected microbial flora in sulphite spent liquor recipients.

摘要

研究了木素磺酸对大肠杆菌素、噬菌体、不同抗生素、金黄色葡萄球菌的β毒素、产气荚膜梭菌和蜡样芽孢杆菌的卵磷脂酶、蜡样芽孢杆菌和大肠杆菌的溶血素、溶血卵磷脂的杀菌作用以及对特异性和天然存在的血清蛋白酶抑制剂的影响。结果发现,木素磺酸能明显抑制所测试的生物活性,但血清抗蛋白酶、血清中的天然抑制剂以及噬菌体的溶菌作用可能除外。讨论了这些抑制作用与含有木素磺酸的动物饲料的使用以及亚硫酸盐废液接受器中特定微生物菌群出现的关系。

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The letal action of monofunctional and bifunctional alkylating agents on T7 coliphage.
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本文引用的文献

8
Inhibitory effect of lysolecithin on bacterial growth.溶血卵磷脂对细菌生长的抑制作用。
Acta Pathol Microbiol Scand. 1969;77(2):283-90. doi: 10.1111/j.1699-0463.1969.tb04233.x.

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