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锂在大鼠体内的分布及其对其他离子分布和排泄的影响。

The distribution of lithium and its effects on the distribution and excretion of other ions in the rat.

作者信息

Birch N J, Jenner F A

出版信息

Br J Pharmacol. 1973 Mar;47(3):586-94. doi: 10.1111/j.1476-5381.1973.tb08189.x.

Abstract
  1. In rats, lithium (ca 1 mEquiv/kg body weight) decreased brain sodium and magnesium, bone sodium and calcium and increased muscle calcium, plasma magnesium, urinary calcium and urine volume.2. Lithium was particularly concentrated in bone.
摘要
  1. 在大鼠中,锂(约1毫当量/千克体重)降低了脑内的钠和镁、骨骼中的钠和钙,并增加了肌肉中的钙、血浆镁、尿钙和尿量。2. 锂特别集中在骨骼中。

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本文引用的文献

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MAGNESIUM--LITHIUM STUDIES 1. SERUM AND ERYTHROCYTE MAGNESIUM IN PATIENTS WITH MANIC STATES DURING LITHIUM TREATMENT.
Acta Psychiatr Scand. 1964;40(2):190-6. doi: 10.1111/j.1600-0447.1964.tb05745.x.
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Metabolic balance studies on the effect of lithium salts in manic-depressive psychosis.
Br J Psychiatry. 1968 Dec;114(517):1561-73. doi: 10.1192/bjp.114.517.1561.
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