Callaghan N, Kearney B, Love W C
J Neurol Neurosurg Psychiatry. 1973 Aug;36(4):668-73. doi: 10.1136/jnnp.36.4.668.
The linoleic acid intake of patients with multiple sclerosis is not significantly different from that of healthy control subjects. This is true both in absolute terms and when linoleic acid intake is expressed as a percentage of total fat intake. In the other categories of illness, included as control groups, linoleic acid intake was significantly decreased only in patients with acute non-neurological illness and in this case only when considered in absolute terms. In all groups studied the daily linoleic acid intake was in excess of 1·7% of the total calorie intake and in the case of multiple sclerosis was 2·7% of the total calories ingested. Since other workers have shown that linoleic acid absorption is not altered in multiple sclerosis and we have shown that the diet is not deficient, it seems that the decrease in linoleic acid content is due to some process occurring after the absorption of this essential fatty acid.
多发性硬化症患者的亚油酸摄入量与健康对照受试者相比无显著差异。无论是从绝对值来看，还是将亚油酸摄入量表示为总脂肪摄入量的百分比时，都是如此。在作为对照组纳入的其他疾病类别中，仅急性非神经系统疾病患者的亚油酸摄入量显著降低，且仅在从绝对值考虑时才如此。在所有研究组中，每日亚油酸摄入量均超过总热量摄入的1.7%，而多发性硬化症患者的这一比例为摄入总热量的2.7%。由于其他研究人员已表明多发性硬化症患者的亚油酸吸收未发生改变，且我们已表明饮食并无缺乏，因此亚油酸含量的降低似乎是由于这种必需脂肪酸吸收后发生的某种过程所致。
