多发性硬化症及其他疾病中血清脂质的亚油酸和脂肪酸模式
Linoleate and fatty-acid patterns of serum lipids in multiple sclerosis and other diseases.
作者信息
Love W C, Cashell A, Reynolds M, Callaghan N
出版信息
Br Med J. 1974 Jul 6;3(5922):18-21. doi: 10.1136/bmj.3.5922.18.
Abstract
The linoleic acid content of serum lipids was measured in 47 patients with multiple sclerosis, 29 patients with other neurological diseases, 35 patients with acute non-neurological illnesses, and 49 healthy control subjects. Reduced linoleic acid content of serum lipids was not specific to multiple sclerosis and occurred in all ill patients with acute non-neurological illness. The fatty-acid pattern of serum lipids in illness resembles that of essential fatty-acid deficiency. It seems that this pattern of reduced linoleic acid content with increased oleic, palmitic, and palmitoleic acid content may be a general phenomenon in ill patients.
摘要
对47例多发性硬化症患者、29例患有其他神经系统疾病的患者、35例患有急性非神经系统疾病的患者以及49名健康对照者的血清脂质亚油酸含量进行了测量。血清脂质亚油酸含量降低并非多发性硬化症所特有，在所有患有急性非神经系统疾病的患者中均有出现。患病时血清脂质的脂肪酸模式类似于必需脂肪酸缺乏的模式。似乎这种亚油酸含量降低、油酸、棕榈酸和棕榈油酸含量增加的模式可能是患病患者中的普遍现象。
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