过滤性白细胞去除术：粒细胞计数对供体采集量的影响。
Filtration leukapheresis: the influence of granulocyte counts upon the donors' yield.
作者信息
Kosmidis P A, Lewandowski S
出版信息
Transfusion. 1979 Jul-Aug;19(4):475-9. doi: 10.1046/j.1537-2995.1979.19479250187.x.
The purpose of this investigation was to determine the influence of granulocyte count on the yield of granulocytes. Healthy adult volunteer donors underwent filtration leukapheresis without premedication. The granulocyte count was measured before and immediately after the procedure. In 73 donors, there was an increase and in 67 donors there was a decrease in the granulocyte counts. In this study of nonmedicated donors those with high initial granulocytes counts and those in which there was a large increase in the postleukapheresis granulocyte counts provided the best yield with the filtration leukapheresis technique.
本研究的目的是确定粒细胞计数对粒细胞采集量的影响。健康成年志愿者捐献者在未进行预处理的情况下接受过滤白细胞单采术。在手术前和手术后立即测量粒细胞计数。73名捐献者的粒细胞计数增加，67名捐献者的粒细胞计数减少。在这项针对未用药捐献者的研究中，初始粒细胞计数高的捐献者以及白细胞单采术后粒细胞计数大幅增加的捐献者，采用过滤白细胞单采术可获得最佳采集量。
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