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先天性心脏病患者胸腺中生发中心的发生率。

The incidence of germinal centres in thymus glands of patients with congenital heart disease.

作者信息

Vetters M, Barclay R S

出版信息

J Clin Pathol. 1973 Aug;26(8):583-91. doi: 10.1136/jcp.26.8.583.

DOI:10.1136/jcp.26.8.583
PMID:4733862
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC477829/
Abstract

The incidence of thymic germinal centres in normal individuals is disputed by various authors. The present study gives the results of a detailed histological assessment of 75 thymic biopsies obtained during operations to correct congenital heart lesions. Serial sectioning showed structures previously of disputed significance to be obliquely sectioned germinal centres. Comparison with the data of Hammar (1926) showed that there was some stress involution of the glands studied. Despite this 40% of the subjects had thymic germinal centres. Germinal centres were not detected in subjects under 4 years of age and there were insufficient subjects over 16 years of age to allow assessment of the frequency in adult thymus glands.

摘要

正常个体中胸腺生发中心的发生率存在不同作者的争议。本研究给出了对75例先天性心脏病变手术中获取的胸腺活检组织进行详细组织学评估的结果。连续切片显示，以前意义有争议的结构是斜切的生发中心。与哈马尔（1926年）的数据比较表明，所研究的腺体存在一定程度的应激性退化。尽管如此，40%的受试者有胸腺生发中心。4岁以下的受试者未检测到生发中心，16岁以上的受试者数量不足，无法评估成人胸腺中其出现频率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a6f/477829/a36a91d5bc92/jclinpath00118-0036-a.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a6f/477829/a36a91d5bc92/jclinpath00118-0036-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a6f/477829/da6a9c7d400c/jclinpath00118-0031-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a6f/477829/6edb8a8b2b31/jclinpath00118-0031-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a6f/477829/a3e9f5b3acd2/jclinpath00118-0031-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a6f/477829/86dc2f406265/jclinpath00118-0032-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a6f/477829/9842ed6744eb/jclinpath00118-0032-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a6f/477829/89b8fd2098c6/jclinpath00118-0034-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a6f/477829/1fde69c9bc0c/jclinpath00118-0034-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a6f/477829/b51b281ee90f/jclinpath00118-0034-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a6f/477829/abf31cf4dfd0/jclinpath00118-0034-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a6f/477829/21895db0cd22/jclinpath00118-0035-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a6f/477829/ce9b6fefd094/jclinpath00118-0035-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a6f/477829/de753d5edbd5/jclinpath00118-0035-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a6f/477829/a36a91d5bc92/jclinpath00118-0036-a.jpg

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本文引用的文献

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HISTOLOGY OF A THYMUS REMOVED SURGICALLY FROM A PATIENT WITH SEVERE UNTREATED SYSTEMIC LUPUS ERYTHEMATOSUS.从一名未经治疗的重症系统性红斑狼疮患者身上手术切除的胸腺组织学研究。
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