重症肌无力：与胸腺切除术相关的临床和组织学特征
Myasthenia gravis: clinical and histological features in relation to thymectomy.
作者信息
Sambrook M A, Reid H, Mohr P D, Boddie H G
出版信息
J Neurol Neurosurg Psychiatry. 1976 Jan;39(1):38-43. doi: 10.1136/jnnp.39.1.38.
Abstract
The clinical and thymic histological features of 23 patients who underwent thymectomy for myasthenia gravis have been examined and compared. Eighty-two per cent of patients with a non-neoplastic gland containing numerous germinal centres improved postoperatively, whereas 83% of patients with a non-neoplastic gland containing no germinal centres deteriorated or died. Glands with only slight involution and containing numerous germinal centres were more commonly seen in young female patients. The evidence relating thymic histological appearances with the postoperative progress of patients with myasthenia gravis is reviewed.
摘要
对23例因重症肌无力接受胸腺切除术的患者的临床和胸腺组织学特征进行了检查和比较。非肿瘤性腺体含有大量生发中心的患者中，82%术后病情改善，而腺体不含生发中心的非肿瘤性腺体患者中，83%病情恶化或死亡。仅轻度退化且含有大量生发中心的腺体在年轻女性患者中更为常见。本文综述了胸腺组织学表现与重症肌无力患者术后病情进展之间的相关证据。
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