Emery J L, Dinsdale F
J Clin Pathol. 1973 Jul;26(7):539-45. doi: 10.1136/jcp.26.7.539.
A quantitative study has been made of standardized sections taken from the right middle lobe of 316 children's lungs. Lungs showing no pathological state showed that lymph nodes are present at birth and these increase in prominence if not in numbers throughout the first year after birth. Lymphoreticular aggregates are not present among the alveoli of the normal infant lung at birth. These first appear around a week after birth and progressively increase in number throughout infancy and early childhood, being almost universally present by the age of 5 years. The development of peripheral lymphoreticular aggregates in the lungs of infants appears to be entirely environmentally and antigenically stimulated.
对取自316名儿童右中叶肺的标准化切片进行了定量研究。无病理状态的肺显示，淋巴结在出生时就已存在，并且在出生后的第一年中，即使数量没有增加，其突出程度也会增加。正常婴儿出生时肺的肺泡中不存在淋巴网状聚集体。这些聚集体在出生后约一周首次出现，并在整个婴儿期和幼儿期数量逐渐增加，到5岁时几乎普遍存在。婴儿肺部外周淋巴网状聚集体的发育似乎完全是由环境和抗原刺激引起的。
