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[移植器官培养后大鼠同种和异种移植中上颈神经节的细胞超微结构]

[Cellular ultrastructure of the superior cervical ganglion of the rat in homo- and heterografts following organ culture of the transplant].

作者信息

Coujard M F

出版信息

Z Mikrosk Anat Forsch. 1979;93(1):33-50.

PMID:473860
Abstract

Transplantation of the superior cervical ganglion of rat, after by organe culture retains ultrastructural integrity of the cells for a longer period than transplantation alone. Whatever the graft--homo or heterograft--neuronal survival is extended. Apart from minuts differences, S.I.F. cells show the same evolution. Ultrastructural features modified after culture always return to their initial state. Numerous after the culture always return to their initial state. Numerous after the culture, the lysosomes disappear in the first weeks following the graft. This cytoplasmic epuration is very important, since it might regenerate the cell and dilate its antigenic properties. Without the graft, the cytoplasmic epuration does not take place; vascularization is considered as a favourable factor of evolution. The association graft-culture has a double impact on survival of SCG cells. The culture initiates a cellular epuration, the graft quickens and perfects the return to a normal morphology.

摘要

大鼠颈上神经节经器官培养后进行移植,其细胞超微结构完整性的保持时间比单纯移植更长。无论移植的是同种异体还是异种移植物,神经元的存活时间都会延长。除了细微差异外,S.I.F. 细胞也呈现相同的演变过程。培养后改变的超微结构特征总是会恢复到初始状态。培养后大量的溶酶体在移植后的最初几周内消失。这种细胞质净化非常重要,因为它可能使细胞再生并扩展其抗原特性。没有移植时,细胞质净化不会发生;血管化被认为是一个有利的演变因素。移植与培养的联合对颈上神经节细胞的存活有双重影响。培养启动细胞净化,移植加速并完善向正常形态的恢复。

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