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Three new adenosine triphosphate analogs. Synthesis and effects on isolated gut.

作者信息

Gough G R, Maguire M H, Satchell D G

出版信息

J Med Chem. 1973 Oct;16(10):1188-90. doi: 10.1021/jm00268a028.

DOI:10.1021/jm00268a028
PMID:4749478
Abstract
摘要

相似文献

1
Three new adenosine triphosphate analogs. Synthesis and effects on isolated gut.三种新型三磷酸腺苷类似物。合成及其对离体肠道的作用。
J Med Chem. 1973 Oct;16(10):1188-90. doi: 10.1021/jm00268a028.
2
The contribution of adenosine to the inhibitory actions of adenine nucleotides on the guinea-pig taenia coli: studies with phosphate-modified adenine nucleotide analogs and dipyridamole.腺苷对腺嘌呤核苷酸抑制豚鼠结肠带作用的贡献：使用磷酸修饰的腺嘌呤核苷酸类似物和双嘧达莫的研究
J Pharmacol Exp Ther. 1979 Dec;211(3):626-31.
3
Inhibitory effects of adenine nucleotide analogs on the isolated guinea-pig taenia coli.腺嘌呤核苷酸类似物对离体豚鼠结肠带的抑制作用。
J Pharmacol Exp Ther. 1975 Dec;195(3):540-8.
4
Dual action of high energy adenine nucleotides in comparison with responses evoked by other adenine derivatives and intramural nerve stimulation on smooth muscle.与其他腺嘌呤衍生物及壁内神经刺激对平滑肌所诱发的反应相比，高能腺嘌呤核苷酸的双重作用。
Eur J Pharmacol. 1981 Sep 11;74(2-3):175-80. doi: 10.1016/0014-2999(81)90528-8.
5
Comparison of the inhibitory effects on the guinea-pig taenia coli of adenine nucleotides and adenosine in the presence and absence of dipyridamole.在有和没有双嘧达莫存在的情况下，腺嘌呤核苷酸和腺苷对豚鼠结肠带的抑制作用比较。
Eur J Pharmacol. 1975 Jun-Jul;32(02):324-8. doi: 10.1016/0014-2999(75)90299-x.
6
-Fluoroadenosine triphosphate. Synthesis, properties, and interaction with myosin and heavy meromyosin.-氟代三磷酸腺苷。合成、性质以及与肌球蛋白和重酶解肌球蛋白的相互作用。
Biochemistry. 1972 Jul 18;11(15):2863-71. doi: 10.1021/bi00765a020.
7
Further comparison of contractions of the smooth muscle of the guinea-pig isolated vas deferens induced by ATP and related analogs.对ATP及相关类似物诱导的豚鼠离体输精管平滑肌收缩的进一步比较。
Eur J Pharmacol. 1986 Oct 7;129(3):279-91. doi: 10.1016/0014-2999(86)90438-3.
8
Regulation of adenylate deaminase from Ehrlich ascites-tumour cells by a phosphonate analogue of adenosine triphosphate.三磷酸腺苷的膦酸类似物对艾氏腹水瘤细胞中腺苷脱氨酶的调节作用
Biochem J. 1967 Jul;104(1):10C-12C. doi: 10.1042/bj1040010c.
9
The effects of extracellularly applied ATP and related compounds on electrical and mechanical activity of the smooth muscle taenia coli from the guinea-pig.细胞外施加的ATP及相关化合物对豚鼠结肠带平滑肌电活动和机械活动的影响。
Acta Physiol Scand. 1969 Jan-Feb;75(1):149-56. doi: 10.1111/j.1748-1716.1969.tb04366.x.
10
Comparison of contractions of the smooth muscle of the guinea-pig vas deferens induced by ATP and related nucleotides.ATP及相关核苷酸对豚鼠输精管平滑肌收缩作用的比较
Eur J Pharmacol. 1982 Jul 9;81(2):193-204. doi: 10.1016/0014-2999(82)90437-x.

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That was then, this is now: the development of our knowledge and understanding of P2 receptor subtypes.那是过去，现在不同了：我们对 P2 受体亚型的认识和理解的发展。
Purinergic Signal. 2021 Mar;17(1):9-23. doi: 10.1007/s11302-021-09763-0. Epub 2021 Feb 1.
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Medicinal chemistry of P2 and adenosine receptors: Common scaffolds adapted for multiple targets.P2 和腺苷受体的药物化学：为多个靶点改编的常见支架。
Biochem Pharmacol. 2021 May;187:114311. doi: 10.1016/j.bcp.2020.114311. Epub 2020 Oct 29.
3
Comparative studies on the affinities of ATP derivatives for P2x-purinoceptors in rat urinary bladder.
大鼠膀胱中ATP衍生物对P2x嘌呤受体亲和力的比较研究。
Br J Pharmacol. 1994 Aug;112(4):1151-9. doi: 10.1111/j.1476-5381.1994.tb13204.x.
4
Inhibition of rat colon contractility by prostacyclin (IP-) receptor agonists: involvement of NANC neurotransmission.前列环素（IP-）受体激动剂对大鼠结肠收缩性的抑制作用：非肾上腺素能非胆碱能神经传递的参与
Br J Pharmacol. 1995 May;115(1):163-71. doi: 10.1111/j.1476-5381.1995.tb16334.x.
5
Specific but noncompetitive inhibition by 2-alkylthio analogues of adenosine 5'-monophosphate and adenosine 5'-triphosphate of human platelet aggregation induced by adenosine 5'-diphosphate.5'-二磷酸腺苷诱导的人血小板聚集受到5'-单磷酸腺苷和5'-三磷酸腺苷的2-烷硫基类似物的特异性而非竞争性抑制。
Br J Pharmacol. 1982 Feb;75(2):397-400. doi: 10.1111/j.1476-5381.1982.tb08800.x.
6
Studies on the stereoselectivity of the P2-purinoceptor.P2嘌呤受体的立体选择性研究。
Br J Pharmacol. 1983 Aug;79(4):907-13. doi: 10.1111/j.1476-5381.1983.tb10535.x.
7
Adenosine 5-diphosphate antagonists and human platelets: no evidence that aggregation and inhibition of stimulated adenylate cyclase are mediated by different receptors.腺苷5-二磷酸拮抗剂与人类血小板：无证据表明聚集和刺激型腺苷酸环化酶的抑制作用由不同受体介导。
Br J Pharmacol. 1982 May;76(1):221-7. doi: 10.1111/j.1476-5381.1982.tb09210.x.
8
Evidence for two different P2-purinoceptors on beta cell and pancreatic vascular bed.β细胞和胰腺血管床存在两种不同P2嘌呤受体的证据。
Br J Pharmacol. 1987 Aug;91(4):783-7. doi: 10.1111/j.1476-5381.1987.tb11276.x.
9
Regulation of P2y-purinoceptor-mediated prostacyclin release from human endothelial cells by cytoplasmic calcium concentration.细胞质钙浓度对人内皮细胞中P2y嘌呤受体介导的前列环素释放的调节作用。
Br J Pharmacol. 1988 Dec;95(4):1181-90. doi: 10.1111/j.1476-5381.1988.tb11754.x.
10
Extracellular ATP: effects, sources and fate.细胞外ATP：作用、来源及去向
Biochem J. 1986 Jan 15;233(2):309-19. doi: 10.1042/bj2330309.