Simmons F B
Ann Otol Rhinol Laryngol. 1979 Jul-Aug;88(4 Pt 1):533-9. doi: 10.1177/000348947908800416.
Each of five cats (one congenitally deaf) had Pt-Ir electrodes placed in the modiolus. Some electrodes were stimulated with a 100 micronamp, 0.25 msec balanced biphasic 50/sec pulse for 2 hours for a total of 20 to 40 hours each over periods of several months. Pre- and poststimulation measures of click-evoked N1 responses, averaged brain stem potentials, and impedances showed no long-term effects of damage to the nerves. Light microscopy showed very acceptable tissue tolerance and no evidence of damage caused by electrical stimulation. The deaf cat had about 10% residual nerve fibers which responded to stimulation.
五只猫（其中一只先天性耳聋）每只都在蜗轴中植入了铂铱电极。一些电极用100微安、0.25毫秒、50赫兹的平衡双相脉冲刺激2小时，在几个月的时间里，每只猫总共刺激20至40小时。点击诱发的N1反应、平均脑干电位和阻抗的刺激前后测量结果显示，神经损伤没有长期影响。光学显微镜显示组织耐受性非常良好，没有电刺激造成损伤的迹象。那只耳聋的猫有大约10%的残余神经纤维对刺激有反应。
