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General biological effects of TCDD in laboratory animals.2,3,7,8-四氯二苯并对二恶英在实验动物中的一般生物学效应。
Environ Health Perspect. 1973 Sep;5:101-9. doi: 10.1289/ehp.7305101.
2
Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the immune system of laboratory animals.2,3,7,8-四氯二苯并对二恶英对实验动物免疫系统的影响。
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Pathologic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals.2,3,7,8-四氯二苯并对二恶英对实验动物的病理影响。
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4
Carcinogenesis bioassay of chlorinated dibenzodioxins and related chemicals.氯化二苯并二恶英及相关化学品的致癌生物测定
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5
Toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin.
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Ultrastructural changes in rat liver cells following a single oral dose of TCDD.单次口服二噁英后大鼠肝细胞的超微结构变化。
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Toxicity of chlorinated phenoxy acids in combination with 2,3,7,8-tetrachlorodibenzo-p-dioxin in C57BL/6 male mice.氯代苯氧基酸与2,3,7,8-四氯二苯并对二恶英联合对C57BL/6雄性小鼠的毒性
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Mechanisms of the biological effects of PCBs, polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in experimental animals.多氯联苯、多氯二苯并 - 对 - 二噁英和多氯二苯并呋喃在实验动物中的生物学效应机制
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The Aryl Hydrocarbon Receptor in Energy Balance: The Road from Dioxin-Induced Wasting Syndrome to Combating Obesity with Ahr Ligands.芳香烃受体在能量平衡中的作用:从二恶英诱导的消耗综合征到用 Ahr 配体对抗肥胖。
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2,3,7,8-Tetrachlorodibenzo-p-dioxin abolishes circadian regulation of hepatic metabolic activity in mice.2,3,7,8-四氯二苯并对二恶英可破坏小鼠肝脏代谢活性的昼夜节律调节。
Sci Rep. 2019 Apr 24;9(1):6514. doi: 10.1038/s41598-019-42760-3.
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Targeted deletion of the aryl hydrocarbon receptor in dendritic cells prevents thymic atrophy in response to dioxin.树突状细胞中芳香烃受体的靶向缺失可防止二恶英引起的胸腺萎缩。
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Dioxin-induced increase in leukotriene B4 biosynthesis through the aryl hydrocarbon receptor and its relevance to hepatotoxicity owing to neutrophil infiltration.二噁英通过芳烃受体诱导白三烯B4生物合成增加及其与中性粒细胞浸润所致肝毒性的相关性。
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Systemic and myelotoxic effects of single administration of 2,3,7,8-tetrabromodibenzo-p-dioxin in rats.2,3,7,8-四溴二苯并对二噁英单次给药对大鼠的全身和骨髓毒性作用。
Environ Health Prev Med. 2006 May;11(3):136-44. doi: 10.1265/ehpm.11.136.
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Analysis of dioxins in contaminated soils with the calux and caflux bioassays, an immunoassay, and gas chromatography/high-resolution mass spectrometry.采用CALUX和CAFLUX生物测定法、免疫测定法以及气相色谱/高分辨率质谱法分析污染土壤中的二噁英。
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8
Immunotoxic effects of exposure of rats to xenobiotics via maternal lactation. Part I 2,3,7,8-tetrachlorodibenzo-p-dioxin.大鼠通过母体哺乳接触外源性物质的免疫毒性作用。第一部分 2,3,7,8-四氯二苯并对二恶英。
Int J Exp Pathol. 1995 Dec;76(6):425-39.
9
2,3,7,8-Tetrachlorodibenzo-p-dioxin toxic effects and tissue levels in animals from the contaminated area of Seveso, Italy.2,3,7,8-四氯二苯并对二恶英对意大利塞韦索污染地区动物的毒性作用及组织水平
Arch Environ Contam Toxicol. 1980;9(5):569-77. doi: 10.1007/BF01056936.
10
Long-term hazards of polychlorinated dibenzodioxins and polychlorinated dibenzofurans.多氯二苯并二恶英和多氯二苯并呋喃的长期危害。
Environ Health Perspect. 1980 Jun;36:221-40. doi: 10.1289/ehp.8036221.

本文引用的文献

1
Organs as targets of "dioxin" (2,3,7,8-tetrachlorodibenzo-p-dioxin) intoxication.作为“二噁英”(2,3,7,8-四氯二苯并对二噁英)中毒靶器官的各器官
Naturwissenschaften. 1972 Apr;59(4):174-5. doi: 10.1007/BF00637374.
2
Pathologic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals.2,3,7,8-四氯二苯并对二恶英对实验动物的病理影响。
Environ Health Perspect. 1973 Sep;5:125-40. doi: 10.1289/ehp.7305125.
3
Hematologic and clinical chemistry effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals.2,3,7,8-四氯二苯并对二恶英对实验动物的血液学和临床化学影响。
Environ Health Perspect. 1973 Sep;5:111-8. doi: 10.1289/ehp.7305111.
4
Effect of tetrachlorodibenzo-p-dioxin on growth rate and the synthesis of lipids and proteins in rats.
Bull Environ Contam Toxicol. 1972 Jan;7(1):45-51. doi: 10.1007/BF01709175.
5
Effect of 2,3,7,8-tetrachlorodibenzo-1,4-dioxin on drug metabolism in the rat.
Biochem Pharmacol. 1972 Dec 1;21(23):3196-8. doi: 10.1016/0006-2952(72)90149-9.
6
Toxicology of chlorinated dibenzo-p-dioxins.氯代二苯并对二噁英的毒理学
Environ Health Perspect. 1973 Sep;5:87-99. doi: 10.1289/ehp.730587.
7
Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the immune system of laboratory animals.2,3,7,8-四氯二苯并对二恶英对实验动物免疫系统的影响。
Environ Health Perspect. 1973 Sep;5:149-62. doi: 10.1289/ehp.7305149.

General biological effects of TCDD in laboratory animals.

作者信息

Harris M W, Moore J A, Vos J G, Gupta B N

出版信息

Environ Health Perspect. 1973 Sep;5:101-9. doi: 10.1289/ehp.7305101.

DOI:10.1289/ehp.7305101
PMID:4752896
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1474965/
Abstract
摘要