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[Pharmacological and neurochemical effects of clozapine (Leponex): new aspects in the drug therapy of schizophrenia].

作者信息

Bürki H R, Ruch W, Asper H, Baggiolini M, Stille G

出版信息

Schweiz Med Wochenschr. 1973 Dec 1;103(48):1716-24.

PMID:4753069
Abstract
摘要

相似文献

1
[Pharmacological and neurochemical effects of clozapine (Leponex): new aspects in the drug therapy of schizophrenia].氯氮平（利培酮）的药理和神经化学作用：精神分裂症药物治疗的新方面
Schweiz Med Wochenschr. 1973 Dec 1;103(48):1716-24.
2
[Effect of neuroleptic agents in the chronic pharmacological experiment].[抗精神病药物在慢性药理学实验中的作用]
Arzneimittelforschung. 1974 Sep;24(9):1292-4.
3
[Metabolism of dopamine and norepinephrine in rat brain after acute and chronic administration of haloperidol, loxapine and clozapine].[急性和慢性给予氟哌啶醇、洛沙平及氯氮平后大鼠脑内多巴胺和去甲肾上腺素的代谢]
Arzneimittelforschung. 1974 Jul;24(7):983-4.
4
Tolerance phenomena with neuroleptics catalepsy, apomorphine stereotypies and striatal dopamine metabolism in the rat after single and repeated administration of loxapine and haloperidol.洛沙平与氟哌啶醇单次及重复给药后大鼠出现的抗精神病药致僵住症、阿扑吗啡刻板行为及纹状体多巴胺代谢方面的耐受现象。
Eur J Pharmacol. 1973 Jun;22(3):287-94. doi: 10.1016/0014-2999(73)90028-9.
5
Antipsychotic efficacy of clozapine in correlation to changes in catecholamine metabolism in man.氯氮平对人体儿茶酚胺代谢变化的抗精神病疗效相关性
Adv Biochem Psychopharmacol. 1974;9(0):647-57.
6
[Neuropharmacological findings after chronic administration of haloperidol, loxapine and clozapine].[长期服用氟哌啶醇、洛沙平及氯氮平后的神经药理学研究结果]
Arzneimittelforschung. 1974 Jul;24(7):981-3.
7
[Effects of anticholinergics and clozapine on the activation of the striatal dopaminergic system in the rat by haloperidol. Neurochemical findings (author's transl)].[抗胆碱能药物和氯氮平对氟哌啶醇激活大鼠纹状体多巴胺能系统的影响。神经化学研究结果（作者译）]
Arzneimittelforschung. 1976;26(6):1094-6.
8
Effect of clozapine on the turnover of dopamine in the corpus striatum and in the limbic system.氯氮平对纹状体和边缘系统中多巴胺周转的影响。
J Pharm Pharmacol. 1973 Apr;25(4):346-8. doi: 10.1111/j.2042-7158.1973.tb10025.x.
9
Differential effects of antipsychotic and psychotomimetic drugs on neurotensin systems of discrete extrapyramidal and limbic regions.抗精神病药物和拟精神病药物对离散锥体外系和边缘系统神经降压素系统的不同作用。
J Pharmacol Exp Ther. 1994 Jul;270(1):192-7.
10
[Effects of anticholinergics and clozapine on the activation of the striatal dopaminergic system in the rat by haloperidol. Pharmacological findings (author's transl)].[抗胆碱能药物和氯氮平对氟哌啶醇激活大鼠纹状体多巴胺能系统的影响。药理学研究结果（作者译）]
Arzneimittelforschung. 1976;26(6):1092-3.

引用本文的文献

1
Long-term experience with clozapine in Denmark: research and clinical practice.丹麦使用氯氮平的长期经验：研究与临床实践
Psychopharmacology (Berl). 1989;99 Suppl:S92-6. doi: 10.1007/BF00442569.
2
Clozapine--pharmacokinetic investigations and biochemical effects in man.氯氮平——人体药代动力学研究及生化效应
Psychopharmacology (Berl). 1989;99 Suppl:S32-7. doi: 10.1007/BF00442556.
3
Effect of clozapine on the metabolism of serotonin in rat brain.氯氮平对大鼠脑内5-羟色胺代谢的影响。
Psychopharmacologia. 1976;46(1):103-9. doi: 10.1007/BF00421556.
4
The interaction of neuroleptic and muscarinic agents with central dopaminergic systems.抗精神病药物与毒蕈碱剂对中枢多巴胺能系统的相互作用。
Br J Pharmacol. 1975 May;54(1):115-21. doi: 10.1111/j.1476-5381.1975.tb07417.x.
5
Extrapyramidal reactions and amine metabolites in cerebrospinal fluid during haloperidol and clozapine treatment of schizophrenic patients.在精神分裂症患者接受氟哌啶醇和氯氮平治疗期间的锥体外系反应及脑脊液中的胺代谢产物
Psychopharmacologia. 1975;40(4):341-50. doi: 10.1007/BF00421473.
6
Serum concentrations of clozapine determined by nitrogen selective gas chromatography.
Arch Toxicol. 1977 Aug 9;37(4):313-8. doi: 10.1007/BF00330823.
7
On the significance of the increase in homovanillic acid (HVA) caused by antipsychotic drugs in corpus striatum and limbic forebrain.抗精神病药物引起的纹状体和边缘前脑高香草酸（HVA）升高的意义
Psychopharmacologia. 1975 Aug 21;43(2):125-30. doi: 10.1007/BF00421014.
8
Effects of clozapine, thioridazine, perlapine and haloperidol on the metabolism of the biogenic amines in the brain of the rat.氯氮平、硫利达嗪、奋乃静和氟哌啶醇对大鼠脑内生物胺代谢的影响。
Psychopharmacologia. 1975;41(1):27-33. doi: 10.1007/BF00421302.
9
Inhibition of 4,alpha-dimethyl-m-tyramine (H 77/77)-induced hypermotility in rats by single and repeated administration of chloropromazine, haloperidol, clozapine and thioridazine.单次及重复给予氯丙嗪、氟哌啶醇、氯氮平和硫利达嗪对4,α-二甲基间酪氨酸（H 77/77）诱导的大鼠运动亢进的抑制作用
Psychopharmacologia. 1975 Jul 23;43(1):25-9. doi: 10.1007/BF00437610.
10
Anti-dopaminergic and anti-muscarinic effects of dibenzodiazepines: relationship to drug induced Parkinsonism.二苯并二氮䓬类药物的抗多巴胺能和抗毒蕈碱作用：与药物诱发帕金森综合征的关系。
Naunyn Schmiedebergs Arch Pharmacol. 1976;292(3):289-93. doi: 10.1007/BF00517391.