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[维生素 D 缺乏性佝偻病中的红细胞代谢]

[Erythrocyte metabolism in vitamin D deficiency rickets].

作者信息

Alexander M, Mandelbaum I M

出版信息

Ann Endocrinol (Paris). 1979;40(2):169-70.

PMID:475311
Abstract

In an attempt to explain the hemolysis observed in vitamin D deficiency rickets in the infant, we studied erythrocytic glycolysis, the level of ATP and some of the key enzymes of the glycolytic pathway. This study was performed in one group of vitamin D deficient infants and in one control group. The values obtained in these two groups did not differ significantly. In the absence of a defect in the glycolytic pathway, we suggest that an anomaly exists in the red cell membrane of these patients.

摘要

为了解释婴儿维生素D缺乏性佝偻病中观察到的溶血现象,我们研究了红细胞糖酵解、ATP水平以及糖酵解途径的一些关键酶。本研究在一组维生素D缺乏的婴儿和一组对照组中进行。这两组获得的值没有显著差异。在糖酵解途径没有缺陷的情况下,我们认为这些患者的红细胞膜存在异常。

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