Nanjappa B N, Chang H K, Glomski C A
Biophys J. 1973 Nov;13(11):1212-22. doi: 10.1016/S0006-3495(73)86056-4.
Studies have been performed on erythrocytes that have been subjected to a low shear stress of less than 100 dyn/cm(2) in a cone-and-plate viscometer. Alterations that were observed included decreased red cell survival, increased osmotic fragility, changes in the cation permeability of the red cell membrane, and a reduction in membrane-associated acetylcholinesterase activity. Some of these alterations are similar to those accompanying aging. The observed data suggest that one segment of the erythrocyte population is more susceptible to shear-induced damage than the rest of the cells.
研究人员已对在锥板式粘度计中承受小于100达因/平方厘米低切应力的红细胞进行了研究。观察到的变化包括红细胞存活期缩短、渗透脆性增加、红细胞膜阳离子通透性改变以及膜相关乙酰胆碱酯酶活性降低。其中一些变化与衰老过程中的变化相似。观察到的数据表明，红细胞群体中的一部分比其他细胞更容易受到剪切诱导的损伤。
