Jones R W, Sharp C, Rabb L R, Lambert B R, Chamberlain D A
Arch Dis Child. 1979 Jun;54(6):427-31. doi: 10.1136/adc.54.6.427.
Electrocardiograms were recorded from 1028 (99.4%) of 1034 consecutively born babies on the 1st or 2nd day of life. Abnormalities of cardiac rhythm or conduction were found in 49 (4.8%) babies. 17 babies had single or multiple premature beats during the recordings, and 7 babies showed sudden increases in R-R interval possibly due to sinoatrial node dysfunction. One baby had sinus or junctional bradycardia of less than 80 beats/min. One baby had an incessant reciprocating tachycardia and subsequently required digoxin for heart failure. Continuous 24-hour ECG monitoring in 25 babies with abnormalities of the screening ECG, and 25 babies without such abnormalities, failed to show any additional tachyarrhythmias or bradyarrhythmias warranting treatment. In view of the uncertain clinical significance of many neonatal arrhythmias and cardiac conduction disorders, more information concerning their natural history and relationship to sudden unexpected death in infancy is needed before recommending that neonatal ECG screening be generally adopted.
对1034例连续出生的婴儿中的1028例(99.4%)在出生后第1天或第2天记录了心电图。发现49例(4.8%)婴儿存在心律失常或传导异常。17例婴儿在记录过程中出现单发性或多发性早搏,7例婴儿显示R-R间期突然延长,可能是由于窦房结功能障碍。1例婴儿出现窦性或交界性心动过缓,心率低于80次/分钟。1例婴儿有持续性折返性心动过速,随后因心力衰竭需要使用地高辛治疗。对25例筛查心电图异常的婴儿和25例无此类异常的婴儿进行连续24小时心电图监测,未发现任何需要治疗的额外快速性心律失常或缓慢性心律失常。鉴于许多新生儿心律失常和心脏传导障碍的临床意义尚不确定,在建议普遍采用新生儿心电图筛查之前,需要更多关于其自然病史以及与婴儿猝死关系的信息。