Keeton B R, Southall E, Rutter N, Anderson R H, Shinebourne E A, Southall D P
Br Med J. 1977 Sep 3;2(6087):600-1. doi: 10.1136/bmj.2.6087.600.
Cardiac conduction disorders caused sudden serious illnesses in six infants that might have been fatal if diagnosis and treatment had been delayed. These cases provide circumstantial evidence to support a link between cardiac conduction disorders and some sudden infant deaths. A further potential long-term effect of these disorders is illustrated in one child in whom psychomotor retardation seemed to develop after an episode of cerebral hypoxia that was probably by an arrhythmia associated with the Wolff-Parkinson-White syndrome. Cardiac conduction disorders may be detected by routine neonatal ECG screening, and it may therefore be appropriate to start prophylactic antiarrhythmic treatment in certain children before clinical signs develop.
心脏传导障碍在六名婴儿中引发了突发重病,若诊断和治疗延误,这些疾病可能会致命。这些病例提供了间接证据,支持心脏传导障碍与一些婴儿猝死之间存在关联。这些障碍的另一个潜在长期影响在一名儿童身上得到体现,该儿童在一次可能由与 Wolff-Parkinson-White 综合征相关的心律失常导致的脑缺氧发作后,似乎出现了精神运动发育迟缓。心脏传导障碍可通过常规新生儿心电图筛查检测出来,因此在某些儿童出现临床症状之前开始预防性抗心律失常治疗可能是合适的。