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心肌血运重建术中的血液保护

Blood conservation during myocardial revascularization.

作者信息

Cosgrove D M, Thurer R L, Lytle B W, Gill C G, Peter M, Loop F D

出版信息

Ann Thorac Surg. 1979 Aug;28(2):184-9. doi: 10.1016/s0003-4975(10)63778-2.

DOI:10.1016/s0003-4975(10)63778-2
PMID:475490
Abstract

A prospective study of blood utilization in 50 consecutive patients undergoing elective coronary artery bypass was undertaken. Blood was removed from all patients during induction of anesthesia and reinfused after bypass (mean, 675 ml). Intraoperatively, all discard suction was routed through a regionally heparinized collecting and processing system, and the resulting red cell concentrate was transfused. At the conclusion of bypass, all blood remaining in the pump oxygenator was retained for transfusion. After operation, shed mediastinal blood was collected in a sterile, filtered collection system and transfused. Normovolemic anemia was accepted in hemodynamically stable patients. The mean amount of patients' blood salvaged by the intraoperative system was 259 ml (range, 0 to 724 ml) and by the postoperative system, 194 ml (range, 0 to 564 ml). Ninety-four percent (47/50) of the patients received no bank blood or blood products during their hospital stay. No patients received bank blood intraoperatively or during the first 24 hours following operation. There were no complications attributable to blood salvage techniques.

摘要

对50例连续接受择期冠状动脉搭桥手术的患者进行了一项血液利用的前瞻性研究。在麻醉诱导期间从所有患者身上采血,并在体外循环后回输(平均675毫升)。术中,所有废弃的吸引血都通过局部肝素化的收集和处理系统,所得的红细胞浓缩液被输注。体外循环结束时,氧合器泵中剩余的所有血液都留存用于输血。术后,纵隔引流血收集在无菌、过滤的收集系统中并输注。血流动力学稳定的患者接受正常血容量性贫血状态。术中系统回收的患者血液平均量为259毫升(范围为0至724毫升),术后系统回收的为194毫升(范围为0至564毫升)。94%(47/50)的患者在住院期间未接受库存血或血液制品。没有患者在术中或术后头24小时内接受库存血。没有因血液回收技术导致的并发症。

相似文献

1
Blood conservation during myocardial revascularization.心肌血运重建术中的血液保护
Ann Thorac Surg. 1979 Aug;28(2):184-9. doi: 10.1016/s0003-4975(10)63778-2.
2
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3
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Eur J Cardiothorac Surg. 2006 Aug;30(2):271-7. doi: 10.1016/j.ejcts.2006.04.042. Epub 2006 Jul 7.
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Reduction of blood utilization during myocardial revascularization.
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Elective coronary artery bypass surgery without homologous blood transfusion. Early results with an inexpensive blood conservation program.非同源输血的择期冠状动脉搭桥手术。采用低成本血液保护方案的早期结果。
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引用本文的文献

1
Adverse Outcomes of Perioperative Red Blood Cell Transfusions in Coronary Artery Bypass Grafting in Hospital Universiti Sains Malaysia.马来西亚理科大学医院冠状动脉搭桥手术围手术期红细胞输血的不良后果
Malays J Med Sci. 2019 May;26(3):49-63. doi: 10.21315/mjms2019.26.3.4. Epub 2019 Jun 28.
2
Does transfusion of residual cardiopulmonary bypass circuit blood increase postoperative bleeding? A prospective randomized study in patients undergoing on pump cardiopulmonary bypass.输注体外循环回路剩余血液会增加术后出血吗?一项针对接受体外循环心脏手术患者的前瞻性随机研究。
Asian J Transfus Sci. 2008 Jul;2(2):51-5. doi: 10.4103/0973-6247.42659.
3
Homologous blood use and conservation techniques for cardiac surgery in the United Kingdom.
英国心脏手术中的同源血使用与保存技术。
BMJ. 1988 Nov 26;297(6660):1390-1. doi: 10.1136/bmj.297.6660.1390.
4
Blood conservation in cardiac surgery. Preliminary results with an institutional commitment.心脏手术中的血液保护。机构承诺下的初步结果。
Ann Surg. 1989 Jun;209(6):736-42. doi: 10.1097/00000658-198906000-00011.
5
Reoperation for coronary atherosclerosis. Changing practice in 2509 consecutive patients.冠状动脉粥样硬化的再次手术。2509例连续患者的实践变化
Ann Surg. 1990 Sep;212(3):378-85; discussion 385-6. doi: 10.1097/00000658-199009000-00016.