前列腺素15（R）-15-甲基-E2甲酯用于抑制足月孕妇胃酸分泌。
Prostaglandin 15 (R) 15-methyl-E2 methyl ester for suppression of gastric acidity in gravida at term.
作者信息
Amy J J, Jackson D M, Ganesan P A, Karim S M
出版信息
Br Med J. 1973 Oct 27;4(5886):208-11. doi: 10.1136/bmj.4.5886.208.
Abstract
During the second hour after giving 100 mug of orally administered prostaglandin 15 (R) 15-methyl-E(2) methyl ester in the pregnant patient at term a noticeable reduction in basal gastric acid secretion took place. At this dose no excessive uterine stimulation was observed. Prostaglandin 15 (R) 15-methyl-E(2) methyl ester could prove of value in the preoperative preparation of the pregnant patient before anaesthesia for reducing the incidence of acid regurgitation.
摘要
在足月妊娠患者口服100微克前列腺素15（R）15-甲基-E（2）甲酯后的第二个小时，基础胃酸分泌明显减少。在此剂量下未观察到过度的子宫刺激。前列腺素15（R）15-甲基-E（2）甲酯可能在妊娠患者术前麻醉准备中具有降低胃酸反流发生率的价值。
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Prostaglandin 15 (R) 15-methyl-E2 methyl ester for suppression of gastric acidity in gravida at term.前列腺素15（R）-15-甲基-E2甲酯用于抑制足月孕妇胃酸分泌。
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本文引用的文献
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Effect of orally administered prostaglandin E1 on gastric secretion and gastrointestinal motility in man.口服前列腺素E1对人体胃液分泌及胃肠蠕动的影响。
Gut. 1968 Dec;9(6):655-8. doi: 10.1136/gut.9.6.655.
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Effect of prostaglandin E1 on gastric secretion and ulcer formation in the rat.前列腺素E1对大鼠胃液分泌及溃疡形成的影响。
Gastroenterology. 1968 Oct;55(4):481-7.
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[Effect of prostaglandin E 1 on the basal gastric secretion in man].[前列腺素E1对人体基础胃分泌的影响]
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The anaesthetist's contribution to maternal mortality.麻醉医生对孕产妇死亡的影响。
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(15S)-15-methylprostaglandins.（15S）-15-甲基前列腺素
J Am Chem Soc. 1972 May 17;94(10):3651-2. doi: 10.1021/ja00765a078.
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Inhibition of gastric secretion by prostaglandins.前列腺素对胃酸分泌的抑制作用。
Am J Dig Dis. 1967 Oct;12(10):1073-6. doi: 10.1007/BF02233268.
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