心得宁在慢性肾衰竭中的药效学
Pharmacodynamics of practolol in chronic renal failure.
作者信息
Eastwood J B, Curtis J R, Smith R B
出版信息
Br Med J. 1973 Nov 10;4(5888):320-2. doi: 10.1136/bmj.4.5888.320.
Abstract
Plasma levels of practolol were measured in advanced chronic renal failure. The plasma half life was found to be markedly prolonged. During haemodialysis considerable shortening of the half life occurred. Therapeutic blood levels of practolol can be achieved in maintenance haemodialysis patients by the administration of 200 mg of the drug by mouth at the beginning and end of each dialysis.
摘要
在晚期慢性肾衰竭患者中测定了醋氨心安的血浆水平。发现其血浆半衰期明显延长。在血液透析期间，半衰期显著缩短。在每次透析开始和结束时口服200毫克该药物，可使维持性血液透析患者达到醋氨心安的治疗血药浓度。
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2
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Br J Anaesth. 1968 Jul;40(7):508-10. doi: 10.1093/bja/40.7.508.
3
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Clin Sci. 1969 Aug;37(1):169-80.
4
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