Silverberg D S, Allard M J, Ulan R A, Beamish W E, Lentle B C, McPhee M S, Grace M G
Can Med Assoc J. 1973 Nov 17;109(10):981-5.
Screening for urinary tract infection was carried out in 23,427 schoolgirls, aged 5 to 14 years, using Uricult and, for hematuria, glycosuria and proteinuria using Hema-combistix. Cultures of 10(5) colonies per ml. or more on two occasions were obtained in 2.3% and a positive culture was confirmed by the family physician using standard culture techniques in 82.7% of cases, giving an overall incidence of infection of 1.9%. Fifty-eight percent of these children had no previous history of any urinary tract symptoms. Of the infected group 9.5% had pyelonephritic scarring, 58.7% chronic cystitis and 58.7% urethral stenosis. Two additional cases had unilateral ureteropelvic junction obstruction with hydronephrosis. Reflux occurred in 26.6% of those investigated by voiding cystogram. In 58% of cases the urinary tract infection was not accompanied by significant proteinuria, hematuria or pyuria.Proteinuria was detected on two occasions in 1.6% of the children and confirmed by the family physician in 33% of cases, giving an overall incidence of 0.5%. In this group 9.2% had evidence of pyelonephritic scarring without a positive urine culture.Hematuria was detected on two occasions in 0.6% of the children and was confirmed by the family physician in 53%, giving an overall incidence of 0.3%. Only one case with pyelonephritic scarring was seen in this group.Of the 25 cases with pyelonephritic changes only six had been previously diagnosed radiologically.Four previously unrecognized diabetics were also detected.
对23427名5至14岁的女学生进行了尿路感染筛查,采用尿培养法,对于血尿、糖尿和蛋白尿则使用尿潜血试纸条检测。两次培养结果均显示每毫升菌落数达到10(5)个或更多的情况占2.3%,家庭医生采用标准培养技术在82.7%的病例中确认培养结果呈阳性,总体感染发生率为1.9%。这些儿童中有58%既往无任何尿路症状史。在感染组中,9.5%有肾盂肾炎瘢痕形成,58.7%有慢性膀胱炎,58.7%有尿道狭窄。另外有两例存在单侧输尿管肾盂连接部梗阻伴肾积水。在接受排尿性膀胱尿道造影检查的患者中,26.6%出现反流。在58%的病例中,尿路感染未伴有明显的蛋白尿、血尿或脓尿。1.6%的儿童两次检测出蛋白尿,家庭医生在33%的病例中予以确认,总体发生率为0.5%。在该组中,9.2%有肾盂肾炎瘢痕形成的证据但尿培养结果未呈阳性。0.6%的儿童两次检测出血尿,家庭医生在53%的病例中予以确认,总体发生率为0.3%。该组中仅发现一例有肾盂肾炎瘢痕形成。在25例有肾盂肾炎改变的病例中,此前只有6例经影像学诊断。还检测出4例先前未被识别的糖尿病患者。