非出血性损伤对大鼠倾斜时心血管反应的影响。
Effects of non-haemorrhagic injury on the cardiovascular response to tilting in the rat.
作者信息
Little R A
出版信息
Br J Exp Pathol. 1979 Jun;60(3):309-13.
In the unanaesthetized uninjured rat a head-up tilt elicited a pressor response, the magnitude of which was directly related to the angle of tilt. The pressor response was reduced by a 4 h period of bilateral hind-limb ischaemia and by a non-fatal scald, although the slope of the regression line relating percentage rise in mean arterial blood pressure to the angle of tilt was unaltered. The degree of impairment of the response was directly related to the severity of the injury. In the uninjured rat there was a sigmoid relationship between the angle of tilt and the mean heart rate during the tilt. No relationship could be demonstrated between angle of tilt and heart rate in the injured rats.
在未麻醉、未受伤的大鼠中，头高位倾斜会引发升压反应，其幅度与倾斜角度直接相关。双侧后肢缺血4小时和非致命性烫伤会使升压反应减弱，尽管平均动脉血压升高百分比与倾斜角度的回归线斜率未改变。反应受损程度与损伤严重程度直接相关。在未受伤的大鼠中，倾斜角度与倾斜期间的平均心率之间呈S形关系。在受伤的大鼠中，倾斜角度与心率之间未显示出相关性。
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