Guthrie D
Br J Obstet Gynaecol. 1979 Jul;86(7):497-500. doi: 10.1111/j.1471-0528.1979.tb10799.x.
Fifty-four patients with advanced cystadenocarcinoma of the ovary were treated with gestronol (Depostat), 200 mg/week, by intramuscular injection and continuous oral cyclophosphamide, the dose of the latter being varied to maintain the patient's white cell count at about 1.5 x 10(9)/l. A combined partial and complete remission rate of 76 per cent was obtained. The length of survival depended upon the type of remission and the type of remission was markedly affected by the amount of tumour removed at initial laparotomy.
54例晚期卵巢囊腺癌患者接受了炔诺醇（Depostat）治疗，每周肌肉注射200毫克，并持续口服环磷酰胺，后者的剂量根据患者白细胞计数维持在约1.5×10⁹/升进行调整。联合部分缓解和完全缓解率达到76%。生存期取决于缓解类型，而缓解类型受到初次剖腹手术时切除肿瘤量的显著影响。
