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抑郁分类及对苯乙肼反应的预测。

Depressive classification and prediction of response to phenelzine.

作者信息

Paykel E S, Parker R R, Penrose R J, Rassaby E R

出版信息

Br J Psychiatry. 1979 Jun;134:572-81. doi: 10.1192/bjp.134.6.572.

DOI:10.1192/bjp.134.6.572
PMID:476367
Abstract

A variety of depressive classifications were used to predict response to four weeks' treatment with phenelzine. Better response was found in outpatients rather than inpatients, in atypical depressives, in less severe depressives with a pattern of anxiety and other neurotic symptoms, and in groups characterized as hostile and agitated. The findings, although a little patchy, gave clear support to the concept of a specific clinical group responsive to MAO inhibitors.

摘要

使用了多种抑郁分类方法来预测对苯乙肼四周治疗的反应。结果发现,门诊患者而非住院患者、非典型抑郁症患者、伴有焦虑和其他神经症症状模式的病情较轻的抑郁症患者以及具有敌意和烦躁特征的群体,对治疗的反应更好。这些发现虽然有些零散,但明确支持了存在对单胺氧化酶抑制剂有反应的特定临床群体这一概念。

相似文献

1
Depressive classification and prediction of response to phenelzine.抑郁分类及对苯乙肼反应的预测。
Br J Psychiatry. 1979 Jun;134:572-81. doi: 10.1192/bjp.134.6.572.
2
Depression subtypes and response to phenelzine, diazepam, and a placebo. Results of a nine hospital collaborative study.抑郁症亚型与对苯乙肼、地西泮及安慰剂的反应。一项九家医院合作研究的结果。
Arch Gen Psychiatry. 1974 Jan;30(1):66-75. doi: 10.1001/archpsyc.1974.01760070050008.
3
Response to phenelzine and amitriptyline in subtypes of outpatient depression.
Arch Gen Psychiatry. 1982 Sep;39(9):1041-9. doi: 10.1001/archpsyc.1982.04290090035008.
4
Prediction of phenelzine outome in depressives.抑郁症患者中苯乙肼治疗结果的预测
Neuropharmacology. 1978 Dec;17(12):1055-6. doi: 10.1016/0028-3908(78)90034-5.
5
The monoamine oxidase inhibitor, phenelzine, in the treatment of depressive -anxiety states. A controlled clinical trial.单胺氧化酶抑制剂苯乙肼治疗抑郁焦虑状态:一项对照临床试验
Arch Gen Psychiatry. 1973 Sep;29(3):407-13. doi: 10.1001/archpsyc.1973.04200030093015.
6
A clinical trial of phenelzine in anxiety depressive and phobic neuroses.苯乙肼治疗焦虑、抑郁及恐怖性神经症的临床试验。
Br J Psychiatry. 1977 Nov;131:486-92. doi: 10.1192/bjp.131.5.486.
7
Clinical pharmacology of phenelzine.
Arch Gen Psychiatry. 1978 May;35(5):629-35. doi: 10.1001/archpsyc.1978.01770290111010.
8
Phenelzine and imipramine in mood reactive depressives. Further delineation of the syndrome of atypical depression.
Arch Gen Psychiatry. 1989 Sep;46(9):787-93. doi: 10.1001/archpsyc.1989.01810090029005.
9
Monoamine oxidase inhibitors. A review of antidepressant effectiveness.单胺氧化酶抑制剂。抗抑郁效果综述。
Arch Gen Psychiatry. 1979 Jul;36(7):749-60. doi: 10.1001/archpsyc.1979.01780070027003.
10
A guide for drug use in depressive disorders.
Am J Psychiatry. 1974 Feb;131(2):181-5. doi: 10.1176/ajp.131.2.181.

引用本文的文献

1
Shared decision-making in physiotherapy: a cross-sectional study of patient involvement factors and issues in Japan.物理治疗中的共同决策:日本对患者参与因素和问题的横断面研究。
BMC Med Inform Decis Mak. 2023 Jul 24;23(1):135. doi: 10.1186/s12911-023-02208-1.
2
Risk-benefit assessment of newer versus older monoamine oxidase (MAO) inhibitors.新型与传统单胺氧化酶(MAO)抑制剂的风险效益评估
Drug Saf. 1994 Apr;10(4):292-300. doi: 10.2165/00002018-199410040-00003.
3
Adverse effects of antidepressant drugs. Part 2: 'Second generation' antidepressants and rational decision making in antidepressant therapy.
抗抑郁药物的不良反应。第2部分:“第二代”抗抑郁药物与抗抑郁治疗中的合理决策
Drugs. 1981 Apr;21(4):273-82. doi: 10.2165/00003495-198121040-00003.
4
The classification of depression.抑郁症的分类。
Br J Clin Pharmacol. 1983;15 Suppl 2(Suppl 2):155S-159S. doi: 10.1111/j.1365-2125.1983.tb05860.x.
5
Strategies for the drug treatment of depression.抑郁症的药物治疗策略。
Can Med Assoc J. 1984 Feb 15;130(4):383-90.
6
Benzodiazepines in the treatment of depressive, borderline personality, and schizophrenic disorders.苯二氮䓬类药物在治疗抑郁、边缘性人格障碍和精神分裂症中的应用。
Br J Clin Pharmacol. 1981;11 Suppl 1(Suppl 1):17S-22S. doi: 10.1111/j.1365-2125.1981.tb01834.x.
7
Controlled trial of trimipramine, monoamine oxidase inhibitors, and combined treatment in depressed outpatients.曲米帕明、单胺氧化酶抑制剂及联合治疗对门诊抑郁症患者疗效的对照试验。
Br Med J. 1979 Nov 24;2(6201):1315-7. doi: 10.1136/bmj.2.6201.1315.