Schatzberg A F, Cole J O
Br J Clin Pharmacol. 1981;11 Suppl 1(Suppl 1):17S-22S. doi: 10.1111/j.1365-2125.1981.tb01834.x.
The use of benzodiazepines in the treatment of depression, borderline states, and schizophrenia is reviewed. The evidence indicates that any effect the benzodiazepines have in depressed, borderline, or schizophrenic patients is anxiolytic and not specific to the disease state. A strategy is presented for determining the therapeutic range of the benzodiazepines in each specific disorder.
本文综述了苯二氮䓬类药物在抑郁症、边缘性状态和精神分裂症治疗中的应用。证据表明,苯二氮䓬类药物对抑郁症、边缘性状态或精神分裂症患者的任何作用都是抗焦虑的,而非针对疾病本身。本文还提出了一种策略,用于确定苯二氮䓬类药物在每种特定疾病中的治疗范围。