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苯二氮䓬类药物在治疗抑郁、边缘性人格障碍和精神分裂症中的应用。

Benzodiazepines in the treatment of depressive, borderline personality, and schizophrenic disorders.

作者信息

Schatzberg A F, Cole J O

出版信息

Br J Clin Pharmacol. 1981;11 Suppl 1(Suppl 1):17S-22S. doi: 10.1111/j.1365-2125.1981.tb01834.x.

DOI:10.1111/j.1365-2125.1981.tb01834.x
PMID:6133529
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1401646/
Abstract

The use of benzodiazepines in the treatment of depression, borderline states, and schizophrenia is reviewed. The evidence indicates that any effect the benzodiazepines have in depressed, borderline, or schizophrenic patients is anxiolytic and not specific to the disease state. A strategy is presented for determining the therapeutic range of the benzodiazepines in each specific disorder.

摘要

本文综述了苯二氮䓬类药物在抑郁症、边缘性状态和精神分裂症治疗中的应用。证据表明,苯二氮䓬类药物对抑郁症、边缘性状态或精神分裂症患者的任何作用都是抗焦虑的,而非针对疾病本身。本文还提出了一种策略,用于确定苯二氮䓬类药物在每种特定疾病中的治疗范围。

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1
Benzodiazepines in the treatment of depressive, borderline personality, and schizophrenic disorders.苯二氮䓬类药物在治疗抑郁、边缘性人格障碍和精神分裂症中的应用。
Br J Clin Pharmacol. 1981;11 Suppl 1(Suppl 1):17S-22S. doi: 10.1111/j.1365-2125.1981.tb01834.x.
2
Drug therapy in borderline patients.边缘型患者的药物治疗。
Compr Psychiatry. 1984 May-Jun;25(3):249-54. doi: 10.1016/0010-440x(84)90055-5.
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Pharmacotherapy of the borderline patient: a critical review and clinical guidelines.边缘型人格障碍患者的药物治疗:批判性综述与临床指南
Can J Psychiatry. 1989 May;34(4):347-53. doi: 10.1177/070674378903400416.
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The positive effect of alprazolam in the treatment of three patients with borderline personality disorder.阿普唑仑对三名边缘型人格障碍患者治疗的积极效果。
Am J Psychiatry. 1984 Jun;141(6):802-3. doi: 10.1176/ajp.141.6.802.
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Specific anxiety syndromes: current therapeutic options.特定焦虑综合征:当前的治疗选择。
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Pharmacotherapy of borderline disorders.
Compr Psychiatry. 1981 Nov-Dec;22(6):535-43. doi: 10.1016/0010-440x(81)90001-8.
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Decisions about drug therapy--V Models derived from diagnostic frequency patterns.药物治疗决策——基于诊断频率模式的V模型
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[Relation between the effect of tranquilizers and various features of personality structure among patients with borderline states].[边缘状态患者中镇静剂的效果与人格结构的各种特征之间的关系]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1984;84(9):1367-76.
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[Clinico-pharmacological characteristics of combined administration of tranquilizing agents and other psychotropic drugs].[镇静剂与其他精神药物联合使用的临床药理学特征]
Farmakol Toksikol. 1982 May-Jun;45(3):36-41.
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Alprazolam-induced dyscontrol in borderline personality disorder.阿普唑仑诱发的边缘型人格障碍失控状态
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引用本文的文献

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Treatment of depressive outpatients with lorazepam, alprazolam, amytriptyline and placebo.
Psychopharmacology (Berl). 1995 Jul;120(1):109-15. doi: 10.1007/BF02246151.
2
Alprazolam in the treatment of generalized anxiety and panic disorders: a double-blind placebo-controlled study.阿普唑仑治疗广泛性焦虑症和惊恐障碍:一项双盲安慰剂对照研究。
Psychopharmacology (Berl). 1982;77(3):229-33. doi: 10.1007/BF00464571.
3
The use of benzodiazepines in depression.苯二氮䓬类药物在抑郁症中的应用。
Br J Clin Pharmacol. 1985;19 Suppl 1(Suppl 1):31S-35S. doi: 10.1111/j.1365-2125.1985.tb02740.x.

本文引用的文献

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Increase in suicidal thoughts and tendencies. Association with diazepam therapy.自杀念头和倾向增加。与地西泮治疗的关联。
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A controlled comparison of diazepam and amylobarbitone in anxiety states.
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When is a tranquillizer an antidepressant?
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Doxepin vs. chlordiazepoxide: a controlled comparison in neurotic outpatients.
Curr Ther Res Clin Exp. 1968 Oct;10(10):514-9.
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Chlorpromazine-chlordiazepoxide and chlorpromazine-imipramine treatment of newly hospitalized, acutely ill psychiatric patients.氯丙嗪-氯氮卓及氯丙嗪-丙咪嗪对新入院急性病精神病患者的治疗
Curr Ther Res Clin Exp. 1966 Mar;8(3):Suppl:117-52.
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Treatment of hospitalized alcoholics with doxepin and diazepam. A controlled study.
Q J Stud Alcohol. 1971 Mar;32(1):78-81.