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关于葡萄球菌α毒素在膜上定位的免疫学证据。

Immunologic evidence that staphylococcal alpha toxin is oriented on membranes.

作者信息

Lo C Y, Fackrell H B

出版信息

Can J Microbiol. 1979 Jun;25(6):686-92. doi: 10.1139/m79-099.

DOI:10.1139/m79-099
PMID:476546
Abstract

Antibodies to staphylococcal alpha toxin were separated into two distinct populations. One population prevented binding of alpha toxin onto erythrocyte membranes. The other population neutralized after the toxin was bound onto erythrocytes and thereby brought about an indirect hemagglutination reaction. The data suggest that alpha toxin has a membrane-binding region.

摘要

抗葡萄球菌α毒素抗体被分离成两个不同的群体。一个群体可阻止α毒素与红细胞膜结合。另一个群体则在毒素与红细胞结合后将其中和,从而引发间接血凝反应。这些数据表明α毒素具有一个膜结合区域。

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Immunologic evidence that staphylococcal alpha toxin is oriented on membranes.关于葡萄球菌α毒素在膜上定位的免疫学证据。
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引用本文的文献

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Enzyme-linked immunosorbent assay for detection of Staphylococcus aureus alpha-toxin.用于检测金黄色葡萄球菌α毒素的酶联免疫吸附测定
J Clin Microbiol. 1984 Mar;19(3):394-8. doi: 10.1128/jcm.19.3.394-398.1984.
2
Early events in the action of staphylococcal alpha-toxin on the plasma membrane of adrenocortical Y1 tumor cells.葡萄球菌α毒素作用于肾上腺皮质Y1肿瘤细胞质膜的早期事件。
Infect Immun. 1986 Sep;53(3):636-40. doi: 10.1128/iai.53.3.636-640.1986.
3
Reaction of staphylococcal alpha-toxin with peptide-induced antibodies.葡萄球菌α毒素与肽诱导抗体的反应。
Infect Immun. 1989 Dec;57(12):3856-62. doi: 10.1128/iai.57.12.3856-3862.1989.