Katz R, Fischmann A B, Galotto J, Guccio J G, Higgins G A, Ortega L G, West W H, Recant L
Cancer. 1979 Aug;44(2):558-63. doi: 10.1002/1097-0142(197908)44:2<558::aid-cncr2820440224>3.0.co;2-s.
A 54-year-old male with diabetes, weight loss, glossitis and Candidiasis presented with the typical cutaneous eruption of necrolytic migratory erythema. The suspicion of pancreatic glucagonoma was confirmed by an elevated plasma glucagon level. Surgical removal of the pancreatic alpha cell tumor resulted in a complete disappearance of all symptoms. The importance of the recognition of the skin eruption of necrolytic migratory erythema as a clue to the presence of pancreatic glucagonoma is emphasized.
一名54岁男性,患有糖尿病、体重减轻、舌炎和念珠菌病,出现了典型的坏死性游走性红斑皮肤疹。血浆胰高血糖素水平升高证实了对胰高血糖素瘤的怀疑。手术切除胰腺α细胞瘤后,所有症状完全消失。强调了将坏死性游走性红斑皮肤疹识别为胰高血糖素瘤存在线索的重要性。