Logemann J A, Bytell D E
Cancer. 1979 Sep;44(3):1095-105. doi: 10.1002/1097-0142(197909)44:3<1095::aid-cncr2820440344>3.0.co;2-c.
This study examined swallowing transit times and motility problems in three groups of patients following ablative surgery for oropharyngeal carcinoma and in a control group of 10 normal subjects. A total of 30 patients was studied: 10 after anterior floor of mouth resection, 12 after tonsil/base of tongue resection, and 8 after supraglottic laryngectomy. Videofluoroscopic studies of liquid, thin paste, thick paste, and thick paste plus liquid swallows were completed 1 week post-initiation of oral feeding following surgery. From the videotapes, oral and pharyngeal transit times were measured, and motility disturbances were defined during each stage of the swallow. All three types of patients in this study showed severe problems with swallowing. The anterior floor of mouth resection patients had problems with preparation for the swallow and oral transit. Tonsil/base of tongue resection patients had slowing in the preparation for the swallow and in the oral and pharyngeal stages. After supraglottic laryngectomy, patients showed only slight slowing in oral transit and pharyngeal transit as compared to other types of surgical patients.
本研究调查了三组口咽癌切除术后患者以及10名正常受试者组成的对照组的吞咽通过时间和运动功能问题。总共研究了30名患者:10名接受口底前部切除术,12名接受扁桃体/舌根切除术,8名接受声门上喉切除术。在术后开始经口进食1周后,完成了对液体、稀糊、稠糊以及稠糊加液体吞咽的视频荧光透视研究。从录像带中测量口腔和咽部通过时间,并在吞咽的每个阶段确定运动功能障碍。本研究中的所有三种类型患者均表现出严重的吞咽问题。口底前部切除术患者在吞咽准备和口腔通过方面存在问题。扁桃体/舌根切除术患者在吞咽准备以及口腔和咽部阶段出现减慢。与其他类型的手术患者相比,声门上喉切除术后患者仅在口腔通过和咽部通过方面略有减慢。