[从CC57Br品系小鼠自发性淋巴肉瘤中分离出的C型病毒的生化和物理化学特性]
[Biochemical and physiocochemical characteristics of a type C virus isolated from spontaneous lymphosarcoma of CC57Br strain mice].
作者信息
Lovenetskiĭ A N, Kiselev F L, Zaretskiĭ I Z, Irlin I S, Bykovskiĭ A F
出版信息
Vopr Virusol. 1975 Jan-Feb(1):14-20.
The properties of murine oncornavirus produced by cells of spontaneous lymphosarcroma of CC57Br mice are described. In addition to the properties common for C-type RNA tumor viruses such as 60-70 S high molecular weight RNA, the presence of RNA-directed DNA polymerase and murine gs I (intraspecies) antigen and typical morphology in electron microscope, etc., the virus under study is characterized by instability of virions, unusual features of the DNA polymerase system and by the absence of demonstrable oncogenicity either in laboratory animals or in tissue cultures.
本文描述了由CC57Br小鼠自发性淋巴肉瘤细胞产生的鼠类肿瘤病毒的特性。除了具有C型RNA肿瘤病毒的常见特性，如60 - 70S高分子量RNA、RNA指导的DNA聚合酶的存在、鼠类gsI（种内）抗原以及在电子显微镜下的典型形态等，所研究的病毒还具有病毒粒子的不稳定性、DNA聚合酶系统的异常特征，并且在实验动物或组织培养中均未表现出明显的致癌性。
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