Reynolds R D, Kelliher G J, Ritchie D M, Roberts J, Beasley A B
Cardiovasc Res. 1979 Mar;13(3):152-9. doi: 10.1093/cvr/13.3.152.
Myocardial infarction was produced in dogs and cats by occlusion of the left anterior descending coronary artery. Arrhythmia was present in dogs but not in cats 6 to 48 h after occlusion. The absence of arrhythmia in cats was not due to persistent myocardial depressant effects of anaesthesia administered during surgery. Studies in cats with surgically-induced heart block revealed multiple ventricular pacemakers but no change in average ventricular rate following coronary occlusion. These results suggest that sinus overdrive, although not elevated compared with the dog, is sufficient to suppress arrhythmia in the cat. Further, since small dogs developed significantly less arrhythmia than large dogs, heart size may be an additional factor in explaining the absence of arrhythmia in the cat.
通过闭塞左冠状动脉前降支在犬和猫身上诱发心肌梗死。闭塞后6至48小时，犬出现心律失常，而猫未出现。猫未出现心律失常并非由于手术期间使用的麻醉剂具有持续的心肌抑制作用。对手术诱发心脏传导阻滞的猫进行的研究显示，存在多个心室起搏器，但冠状动脉闭塞后平均心室率无变化。这些结果表明，尽管与犬相比窦房结超速驱动未升高，但足以抑制猫的心律失常。此外，由于小型犬发生的心律失常明显少于大型犬，心脏大小可能是解释猫未出现心律失常的另一个因素。
