Kitamura S, Kawashima Y, Shimazaki Y, Mori T, Nakano S, Beppu S, Kozuka T
Circulation. 1979 Oct;60(4):849-55. doi: 10.1161/01.cir.60.4.849.
Funtional characteristics of the single ventricle were studied by means of biplane angiocardiography in 34 patients. Group 1 consisted of 14 patients with normal or increased pulmonary vascular marking on chest film and no pulmonary stenosis. Group 2 included 20 patients with severe angiographic pulmonary stenosis and decreased pulmonary vascular marking. Ventricular volume parameters were calculated according to Simpson's rule and were compared with normal values. The sum of the normal left and right ventricular volumes was assumed to be 100%. In group 1, ventricular end-diastolic volumes averaged 143 +/- 11% and were significantly (p less than 0.001) larger than end-diastolic volumes in group 2 (81 +/- 4%). The presence or absence of severe pulmonary stenosis affecting pulmonary blood flow was a main factor regulating the ventricular chamber size in single ventricle. In both groups, the ejection fraction of a single ventricle was significantly lower than that of a normal left or right ventricle. Ventricular size and function in patients with a single ventricle should be carefully assessed before ventricular septation surgery.
采用双向心血管造影术对34例单心室患者的单心室功能特征进行了研究。第1组由14例胸部X线片显示肺血管纹理正常或增多且无肺动脉狭窄的患者组成。第2组包括20例血管造影显示严重肺动脉狭窄且肺血管纹理减少的患者。根据Simpson法则计算心室容积参数，并与正常值进行比较。假定正常左、右心室容积之和为100%。在第1组中，心室舒张末期容积平均为143±11%，显著高于第2组（81±4%）（p<0.001）。影响肺血流的严重肺动脉狭窄的有无是调节单心室心室腔大小的主要因素。在两组中，单心室的射血分数均显著低于正常左心室或右心室。在进行心室间隔修补手术前，应仔细评估单心室患者的心室大小和功能。
