兔体内白细胞致热原的清除部位。
Sites of clearance of leucocyte pyrogen in the rabbit.
作者信息
Townsend Y, Cranston W I
出版信息
Clin Sci (Lond). 1979 Mar;56(3):265-8. doi: 10.1042/cs0560265.
PMID:477210
Abstract
- The dose-response curve for sustained infusions of leucocyte pyrogen has been demonstrated, and an optimum dose indicated for leucocyte pyrogen clearance experiments. 2. The lungs, liver and small bowel are not significantly involved in removal of leucocyte pyrogen from the circulation in conscious rabbits. 3. A single circulation through one kidney removes up to half of the infused dose of leucocyte pyrogen.
摘要
- 已证实了白细胞热原持续输注的剂量-反应曲线，并指出了白细胞热原清除实验的最佳剂量。2. 在清醒兔中，肺、肝和小肠对循环中白细胞热原的清除作用不显著。3. 白细胞热原单次流经一侧肾脏可清除高达一半的输注剂量。
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