参与嘌呤核苷酸从头生物合成的一种酶对，即磷酸核糖氨基咪唑羧化酶和磷酸核糖氨基咪唑琥珀酰胺羧酰胺合成酶的纯化及性质
Purification and properties of an enzyme duet, phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthetase, involved in the biosynthesis of purine nucleotides de novo.
作者信息
Patey C A, Shaw G
出版信息
Biochem J. 1973 Nov;135(3):543-5. doi: 10.1042/bj1350543.
Abstract
Purification and some properties of an adjacent pair of enzymes in the biosynthetic pathway to AMP, phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) and phosphoribosylaminoimidazolesuccinocarboxamide synthetase (EC 6.3.2.6), are described. The enzymes form a duet, which may be regarded as a single molecule with a dual function, or as two very similar substances.
摘要
本文描述了腺苷酸生物合成途径中相邻的一对酶——磷酸核糖氨基咪唑羧化酶（EC 4.1.1.21）和磷酸核糖氨基咪唑琥珀酰胺羧酰胺合成酶（EC 6.3.2.6）的纯化及某些特性。这两种酶形成了一个二重奏，它可以被视为具有双重功能的单个分子，或者是两种非常相似的物质。
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