Lannek B
Acta Vet Scand. 1973 May;14(5):723-44. doi: 10.1186/BF03547401.
A survey of 100 cases of oxyquinoline poisoning in dogs is presented. The disease, characterized by hyperexcitability of the CNS with convulsions as well as heart and liver injury, runs an acute course. The mortality (euthanized dogs included) was 30 Case-history data showed that the oxyquinoline treatment which preceded the disease was given because the dog had incidental diarrhoea. In most cases the drugs were administered for only 1 day before the dog fell ill. The median time from the last dose to onset of symptoms was 12 hrs. Old dogs were affected more often than expected and also showed higher mortality than did young dogs.
本文呈现了对100例犬氧喹啉中毒病例的调查。该病以中枢神经系统兴奋、惊厥以及心脏和肝脏损伤为特征,病程呈急性。死亡率(包括安乐死的犬)为30%。病例史数据显示,在发病前进行氧喹啉治疗是因为犬出现了偶发性腹泻。在大多数情况下,药物仅在犬发病前1天给药。从最后一剂药物到症状出现的中位时间为12小时。老年犬比预期更常受到影响,且死亡率也高于幼犬。