Nove J, Little J B, Weichselbaum R R, Nichols W W, Hoffman E
Cytogenet Cell Genet. 1979;24(3):176-84. doi: 10.1159/000131374.
Five diploid fibroblast strains from patients with deletions mapping in the long arm of chromosome 13 and three strains bearing partial trisomies of chromosome 13 were assayed for clonogenic survival following X-irradiation. Results of these experiments suggest the existence of a region on 13q14 which is related to increased sensitivity to cell killing in vitro by X-rays. This locus seems to be distinct from but close to the retinoblastoma locus, which has been associated with the same band.
对来自13号染色体长臂缺失患者的5个二倍体成纤维细胞系以及携带13号染色体部分三体的3个细胞系进行了X射线照射后的克隆形成存活分析。这些实验结果表明，13q14上存在一个区域，该区域与体外X射线诱导的细胞杀伤敏感性增加有关。这个基因座似乎与视网膜母细胞瘤基因座不同，但与之相邻，视网膜母细胞瘤基因座也与同一染色体带相关。
