[Studies on the effect of 4-methyl-umbelliferon (Hymecromone) in patients following surgical revision of the biliary pathways].

The effect of 4-methylumbelliferone (hymecromone) on postoperative gall volume and residual pressure, serum enzymes, and other parameters in 50 patients after cholecystectomy and choledochotomy with T-tube drainage is measured by a clinical double-blind study. There were several interesting findings: (a) significant less gall flowing from the T tube, (b) highly significant less activity of the enzymes basic phosphatase and of the gamma-glutamyltranspeptidase, and (c) fewer need of analgesics.