Walter P, Seidel W
Chirurg. 1979 Jul;50(7):436-40.
The effect of 4-methylumbelliferone (hymecromone) on postoperative gall volume and residual pressure, serum enzymes, and other parameters in 50 patients after cholecystectomy and choledochotomy with T-tube drainage is measured by a clinical double-blind study. There were several interesting findings: (a) significant less gall flowing from the T tube, (b) highly significant less activity of the enzymes basic phosphatase and of the gamma-glutamyltranspeptidase, and (c) fewer need of analgesics.
通过一项临床双盲研究，测定了4-甲基伞形酮（利胆酚）对50例行胆囊切除术和胆总管切开T管引流术后患者的胆囊容积、残余压力、血清酶及其他参数的影响。有几个有趣的发现：（a）从T管流出的胆汁显著减少；（b）碱性磷酸酶和γ-谷氨酰转肽酶的活性显著降低；（c）镇痛药的需求量减少。
