Schwegler N, Hartweg H
Dtsch Med Wochenschr. 1979 Sep 14;104(37):1297-301. doi: 10.1055/s-0028-1129087.
Distant metastases were sought for in 90 patients with local recurrence of breast carcinoma. Only 11 patients had demonstrable spread of the disease at the time of referral. Two-thirds of all local recurrences presented within two years of the primary operation. In 66 out of 90 patients the recurrence was in the chest wall, in 11 cases it was in the chest wall and in the lymphatic system and in only 13 cases was it primarily in the regional lymph nodes. The recurrence rate depended mainly on the previous treatment of the primary tumour: 42 recurrences were found in those cases treated only by surgery, 46 in cases treated surgically and with low-dose post-operative irradiation and only two in patients treated with over 4500 rad to the area of subsequent recurrence.
对90例局部复发性乳腺癌患者进行了远处转移的检查。转诊时只有11例患者有明确的疾病扩散。所有局部复发中有三分之二发生在初次手术后两年内。90例患者中,66例复发位于胸壁,11例复发于胸壁和淋巴系统,仅13例主要位于区域淋巴结。复发率主要取决于原发肿瘤先前的治疗情况:仅接受手术治疗的患者中有42例复发,接受手术及低剂量术后放疗的患者中有46例复发,而在随后复发区域接受超过4500拉德放疗的患者中仅有2例复发。