Nordman E, Linna M, Nieminen S
Strahlentherapie. 1977 Jan;153(1).
19% of 102 operable cases of breast carcinoma irradiated postoperatively developed local recurrences in the thoracic wall and/or regional lymph nodes during the observation time of five years. Of the 41 radically operated cases of stage I disease only one had recurrence in the chest wall and three metastases in the regional lymph nodes. As the number of local recurrences after mastectomy and evacuation of the axilla combined with postoperative irradiation was fairly small if compared with the results achieved with conservative surgery and irradiation presented in literature, the radical treatment schedule is recommended even in stage I breast carcinoma. The local reappearance of carcinoma is always strenuous for the patient even if the prognosis of a local recurrence after conservative surgery is better than that of the local recurrence after mastectomy.
在102例可手术的乳腺癌病例中,术后接受放疗的患者在五年观察期内,有19%在胸壁和/或区域淋巴结出现局部复发。在41例I期根治性手术的病例中,只有1例胸壁复发,3例区域淋巴结转移。与文献中保守手术加放疗的结果相比,乳房切除加腋窝清扫并术后放疗后的局部复发数量相当少,因此即使是I期乳腺癌,也推荐采用根治性治疗方案。即使保守手术后局部复发的预后优于乳房切除术后局部复发的预后,但癌症的局部再次出现对患者来说总是很痛苦的。