用于治疗尿毒症贫血的组氨酸。
Histidine for treatment of uraemic anaemia.
作者信息
Giordano C, De Santo N G, Rinaldi S, Acone D, Esposito R, Gallo B
出版信息
Br Med J. 1973 Dec 22;4(5894):714-6. doi: 10.1136/bmj.4.5894.714.
A group of 28 uraemic patients on dialysis treatment were given daily supplements of histidine by mouth. Plasma amino-acid concentration, plasma iron, serum transferrin, packed cell volume, and reticulocyte count were all measured before and after two months of histidine supplementation. The treatment raised the plasma histidine concentration and at the same time there was a rise in transferrin and iron levels and packed cell volume. Reticulocyte counts fell after two months of histidine supplementation.
一组28名接受透析治疗的尿毒症患者每天口服补充组氨酸。在补充组氨酸两个月前后，均测量了血浆氨基酸浓度、血浆铁、血清转铁蛋白、红细胞压积和网织红细胞计数。治疗提高了血浆组氨酸浓度，同时转铁蛋白、铁水平和红细胞压积均有所上升。补充组氨酸两个月后，网织红细胞计数下降。
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