Jacobsen J R, Wennevold A, Boesen I
Eur J Cardiol. 1979 Aug;10(2):123-9.
A long-term follow-up study was performed in 14 patients, operated for coarctation of the aorta in infancy. The median age at operation was 4 mth. Mean and median age at follow-up were 16 yr, and the follow-up time varied between 7 and 22 yr (mean and median 15 yr). At follow-up recoarctation was or had been present in 6 patients; there was no relation between the development of recoarctation and the age at operation. Concomitant aortic valve anomaly had been overlooked at the initial investigation in 3 patients. The systolic and diastolic blood pressure at follow-up was significantly elevated above the mean of normals; 2 of 8 patients without recoarctation clearly had diastolic hypertension. It seems as if even operation in infancy does not prevent hypertension later in childhood or adolescence in some of the patients, and it hardly seems justified to perform elective operations for coarctation of the aorta in infancy with the appreciable risk of recoarctation, until more long-term follow-up results are known. The patients should not be lost to follow-up.
对14例婴儿期行主动脉缩窄手术的患者进行了长期随访研究。手术时的中位年龄为4个月。随访时的平均年龄和中位年龄为16岁，随访时间在7至22年之间（平均和中位时间为15年）。随访时，6例患者存在或曾出现再狭窄；再狭窄的发生与手术年龄无关。3例患者在初次检查时漏诊了合并的主动脉瓣异常。随访时的收缩压和舒张压显著高于正常均值；8例无再狭窄的患者中有2例明显患有舒张期高血压。似乎即使在婴儿期进行手术，也不能防止某些患者在儿童期或青少年期后期出现高血压，而且在获得更多长期随访结果之前，鉴于再狭窄有相当大的风险，在婴儿期对主动脉缩窄进行择期手术似乎很难说是合理的。不应遗漏对这些患者的随访。
