兔颈部脂肪组织的血流与脂肪酸释放
Blood flow and fatty acid release by cervical adipose tissue of rabbits.
作者信息
Hardman M J, Hull D
出版信息
J Physiol. 1973 Nov;235(1):1-8. doi: 10.1113/jphysiol.1973.sp010374.
Abstract
- A direct technique was used to measure blood flow and exchange of metabolites by cervical adipose tissue in 3-month-old and adult rabbits.2. The initial blood flow from adipose tissue of fed 3-month-old rabbits was 0.45 ml./g tissue.min and the tissue released fatty acids and glycerol. In similar rabbits unfed for 24 hr, fatty acid release increased fourfold. Both the rate of blood flow and the arterio-venous difference of fatty acid increased. In fed adult rabbits blood flow was 0.16 ml./g tissue.min.3. Noradrenaline infusion in both young and adult rabbits stimulated a rapid and large increase in cervical adipose tissue blood flow together with an increase in fatty acid and glycerol release. Glucose uptake remained small. No increase in local heat production in cervical adipose tissue was detected during noradrenaline infusion.4. It is concluded that cervical adipose tissue in adult rabbits is actively concerned in energy storage and supply.
摘要
采用直接技术测量3月龄和成年兔颈部脂肪组织的血流及代谢物交换情况。
喂食后的3月龄兔脂肪组织的初始血流为0.45毫升/克组织·分钟，该组织释放脂肪酸和甘油。在禁食24小时的同月龄兔中，脂肪酸释放量增加了四倍。血流速率和脂肪酸的动静脉差值均增加。成年喂食兔的血流为0.16毫升/克组织·分钟。
对幼年和成年兔输注去甲肾上腺素均能迅速大幅增加颈部脂肪组织的血流，同时脂肪酸和甘油的释放也增加。葡萄糖摄取量仍较少。输注去甲肾上腺素期间未检测到颈部脂肪组织局部产热增加。
得出结论：成年兔的颈部脂肪组织积极参与能量储存和供应。
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