[急性缺血性心脏病治疗药物对急性营养不良时心肌组织形态学变化的影响]
[Effect of agents used in the therapy of acute ischemic heart disease on the histomorphological changes in the myocardium in acute dystrophy].
作者信息
Nikulin A A, Chernov I P
出版信息
Farmakol Toksikol. 1979 Jul-Aug;42(4):371-6.
The morphological analysis of the portions of the interventricular septum and left ventricular wall in cats has revealed dystrophic and necrotic changes in the myocardium after administration of caffeine followed by adrenaline: haemorrhages, intravascular thrombogenesis, dystrophic and necrobiotic changes in myocytes. In early periods of acute ischemic heart disease morphine, fibrinolysin, heparin and Inosie F either abolished (fibrinolysin) or considerably decreased (heparin and Inosie F) a tendency toward intravascular thrombogenesis and damage to the myocardial parenchyma.
对猫的室间隔和左心室壁部分进行的形态学分析显示，在给予咖啡因后再注射肾上腺素，心肌会出现营养不良和坏死性变化：出血、血管内血栓形成、心肌细胞的营养不良和坏死性变化。在急性缺血性心脏病的早期，吗啡、纤维蛋白溶酶、肝素和肌醇六磷酸要么消除了（纤维蛋白溶酶），要么显著降低了（肝素和肌醇六磷酸）血管内血栓形成的倾向以及心肌实质的损伤。
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