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[安贝维特与奥科明的抗贫血作用]

[Antianemic effect of ampevit and orkomin].

作者信息

Zapadniuk V I, Bezverkhaia I S, Oranskaia S A

出版信息

Farmakol Toksikol. 1979 Jul-Aug;42(4):392-5.

PMID:477961
Abstract

The antianemic action of ampevit and orkomin developed at the Laboratory of Experimental Therapy, Institute of Gerontology, Academy of Medical Sciences of the USSR was studied in experiments on young and old animals. It has been established that repeated administration of the drugs increases the reticulocyte count in both groups of animals. Ampevit diminishes severity of posthemorrhagic anemia. Both drugs promote more rapid recovery of hemoglobin content and red cell count in old animals after blood loss. The data obtained were supported by clinical trials of the drugs which have been recommended for combined treatment of posthemorrhagic anemias and other conditions accompanied by weakened function of the growing red fiber of the bone marrow seen also in people of old and senile age.

摘要

苏联医学科学院老年学研究所实验治疗实验室研发的安珀维特(ampevit)和奥科明(orkomin)的抗贫血作用,在对年轻和老年动物进行的实验中得到了研究。已证实,重复给药会使两组动物的网织红细胞计数增加。安珀维特可减轻失血性贫血的严重程度。两种药物都能促进老年动物失血后血红蛋白含量和红细胞计数更快恢复。所获得的数据得到了这些药物临床试验的支持,这些药物已被推荐用于联合治疗失血性贫血以及其他伴有骨髓新生红细胞纤维功能减弱情况的病症,在老年人和高龄老人中也可见到这种情况。

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